Stock fact sheet · data as of
Aprea Therapeutics, Inc. (APRE): fair value, margin of safety and Wheel Score
Healthcare · Biotechnology · United States · Speculative / Distressed
Is APRE undervalued?
At 0.6176 (close of 16 Oct 2026), APRE trades 71% below the GLS average fair value of 2.14. That average comes from 1 models run on the latest filings, and 1 of them land above the current price. Margins of safety over 30% are the exception rather than the rule across the ~7,400 stocks we value each night, so the number earns Aprea Therapeutics, Inc. the full Value points in the Wheel Score - and a closer look at what the market is pricing in.
Only 1 of the nine models produced a value (DCF); the others need a dividend, positive free cash flow or positive book value the company does not have yet, so the average rests on a narrow base.
The nightly engine files APRE under Speculative / Distressed - negative earnings or a Piotroski score of 3 or less - which caps its Wheel Score at 45 and keeps it out of the Sunday Scan.
Nine valuation models for APRE
Each model turns the latest filed numbers into a value per share; the GLS fair value is the simple average of the ones that produce a positive number. The last two rows are shown for reference and never enter the average. The Quote page lets you switch any model off and add your own margin of safety.
| Model | Value | vs price | What it measures |
|---|---|---|---|
| DCF | 2.14 | +246% | Present value of the projected free cash flows, discounted at the cost of capital |
| Graham Number | - | - | The most a defensive investor pays for the earnings and book value per share; no value tonight |
| Graham Growth | - | - | Graham's growth formula: EPS × (8.5 + 2 × growth), adjusted for bond yields; no value tonight |
| Lynch | - | - | EPS × the earnings growth rate (PEG of 1), growth capped at 25%; no value tonight |
| GLS Growth | - | - | EPS compounded ten years at the blended growth rate, discounted back at 15% a year; no value tonight |
| 10 Cap | - | - | Owner's earnings (operating cash flow less maintenance capex) capitalised at 10%; no value tonight |
| Payback Time | - | - | Eight years of compounded free cash flow: the price at which the business pays for itself; no value tonight |
| DDM | - | - | Dividend discount model: next year's dividend ÷ (10% − 3% growth); needs a dividend; no value tonight |
| EPV | - | - | Earnings power value: current EPS capitalised at 9% with no growth; no value tonight |
| Zombie (liquidation) | 0.9586 | +55% | Current assets less all liabilities, per share: the balance-sheet floor. Not in the average |
| Wall St target | 0.0000 | -100% | Analysts' average 12-month price target. Not in the average |
Quality and financial health
Financial health is weak: APRE passes 3 of the nine Piotroski tests. Our screens drop the stock at the health rule; a low score is often the reason a stock looks cheap on the valuation models. The GLS Moat score is low at 0.9 out of 10, which says the ten-year record of revenue, earnings, margins and returns on capital has been inconsistent - growth and shocks rather than steady compounding.
Returns on capital are thin or negative - ROIC -101.3%, ROE -101.3%, ROA -79.1% - with debt at 0.00 times equity and negative free cash flow.
Aprea Therapeutics, Inc. pays no dividend, so the DDM model does not apply and a covered-call holder earns only the premium and any price gain.
Institutional ownership scores 1/10, insider activity 10/10 and Congressional trading 5/10 on the GLS smart-money scales.
| Piotroski F-score | 3 / 9 | ROIC | -101.3% |
|---|---|---|---|
| GLS Moat | 0.9 / 10 | ROE | -101.3% |
| Debt / equity | 0.00 | ROA | -79.1% |
| Free-cash-flow yield | -156.7% | Payout ratio | 0% |
| Institutions | 1 / 10 | Insiders · Congress | 10 · 5 / 10 |
Wheel Score 38: No options
APRE has no listed options in the nightly snapshot, so there is nothing to sell and the stock cannot be wheeled however good the business; the Wheel Score is capped at 39 and shown as "No options" (38 here). The valuation and quality numbers still apply to owning the shares outright.
Volume runs at 65k shares a day on a market cap of $8M, with a beta of 1.63 - a high beta, so the stock tends to move more than the market and a strike can be gapped through; the Stability part of the Wheel Score gives that 5 of 20.
| Part | Points | From | |
|---|---|---|---|
| Value | 25 / 25 | 71% margin of safety | |
| Health | 7 / 20 | Piotroski 3/9 | |
| Moat | 1 / 15 | moat 0.9/10 | |
| Premium | 0 / 20 | no option data | |
| Stability | 5 / 20 | 65k shares/day, $8M cap, beta 1.63 |
The Wheel Score ranks ~7,400 US stocks for selling cash-secured puts and covered calls; it is updated nightly and is not a recommendation. The walkthrough lesson shows how the score fits into a trade, start to finish.
Upcoming events
The next earnings report is due on 11 Nov 2026 (before the open), 26 days away; a 30-45-day put sold today would expire after it, which is worth weighing against the premium.
Earnings, dividend, IPO, split and economic calendars for the whole market, filterable to your watchlists.
Similar stocks in Biotechnology
The 12 companies below are the closest to Aprea Therapeutics, Inc. by market cap within the Biotechnology industry, each with its own fact sheet; the Compare page puts up to eight of them side by side.
| Stock | Close | Fair value | MoS | Wheel | Mkt cap |
|---|---|---|---|---|---|
| XCUR Exicure, Inc. | 1.21 | 0.3541 | -242% | 4No options | $8M |
| CMMB Chemomab Therapeutics Ltd. | 1.29 | 1.56 | +17% | 28No options | $8M |
| KPTI Karyopharm Therapeutics Inc. | 0.3508 | - | - | 37Weak | $8M |
| CURX Curanex Pharmaceuticals Inc Common Stock | 4.83 | 3.26 | -48% | 13No options | $8M |
| CNSP CNS Pharmaceuticals, Inc. | 5.18 | 7.71 | +33% | 35No options | $8M |
| SNTI Senti Biosciences, Inc. | 0.2408 | - | - | 23No options | $7M |
| SNGX Soligenix, Inc. | 0.3407 | 1.27 | +73% | 35No options | $7M |
| BOLT Bolt Biotherapeutics, Inc. | 4.24 | - | - | 27No options | $8M |
| QNRX Quoin Pharmaceuticals, Ltd. | 4.10 | 2,547.50 | +100% | 35No options | $8M |
| ADIL Adial Pharmaceuticals, Inc. | 3.14 | 7.98 | +61% | 37No options | $8M |
| LTRN Lantern Pharma Inc. | 0.6668 | - | - | 27Weak | $9M |
| AIMD Ainos, Inc. | 0.9600 | - | - | 19No options | $7M |
Screen the whole market the same way
A free GLS Equity account gets you nightly fair value and the Wheel Score on ~7,400 US stocks, a watchlist, the scanner preview and the Sunday Scan - the same eight-rule screen, emailed every week. Pro adds the full put and call scanners, unlimited watchlists with alerts and the trade journal.
Start free See the Sunday ScanQuestions about APRE
Is APRE undervalued right now?
By the GLS models, yes: at 0.6176 the stock is 71% below the average fair value of 2.14 (data as of 16 Oct 2026). Whether the discount is deserved is the question to research next.
What is the Wheel Score of APRE and what does it mean?
APRE has no listed options in our nightly snapshot, so it cannot be wheeled; its Wheel Score is capped at 39 and shown as "No options".
What is the GLS fair value for APRE?
2.14 per share as of 16 Oct 2026 - the simple average of the 1 valuation models (out of nine: DCF, Graham Number, Graham Growth, Lynch, GLS Growth, 10 Cap, Payback Time, DDM and EPV) that produced a positive value. The models run every night on the latest filings; the Quote page lets you switch any of them off and add a margin of safety of your own.
When does Aprea Therapeutics, Inc. report earnings next?
The next earnings report is due on 11 Nov 2026 (before the open), 26 days from the data date of 16 Oct 2026. The Calendars page lists every upcoming report with its time of day.
Does APRE have listed options, and how liquid are they?
No. The nightly options snapshot found no listed contracts on APRE, so the wheel strategy cannot be run on it and the Wheel Score is capped at 39.