Stock fact sheet · data as of

Nautilus Biotechnolgy, Inc. (NAUT): fair value, margin of safety and Wheel Score

Healthcare · Biotechnology · United States · Speculative / Distressed

Close2.16
GLS fair value-no model value
Margin of safety-
Wheel Score40Weakout of 100
Health3/9Piotroski F-score
Moat1.4/10GLS 10-year score
Market cap$275M8.5M shares a day
Implied vol.136%near-the-money, 20-60 d
P/E-EPS -0.45
Dividend yieldnone
Beta0.87about the market
Next earnings26 Oct 2026in 10 days (before the open)

Is NAUT undervalued?

Nautilus Biotechnolgy, Inc. (NAUT) closed at 2.16 on 16 Oct 2026. None of the nine GLS valuation models produced a positive value for the stock - the company lost money over the last twelve months, EPS -0.45 and it pays no dividend - so there is no GLS average fair value and no margin of safety to report. The quality, option and event numbers below still apply; the Quote page's Wall Street View shows what analysts expect instead.

The nightly engine files NAUT under Speculative / Distressed - negative earnings or a Piotroski score of 3 or less - which caps its Wheel Score at 45 and keeps it out of the Sunday Scan.

Nine valuation models for NAUT

Each model turns the latest filed numbers into a value per share; the GLS fair value is the simple average of the ones that produce a positive number. The last two rows are shown for reference and never enter the average. The Quote page lets you switch any model off and add your own margin of safety.

ModelValuevs priceWhat it measures
DCF--Present value of the projected free cash flows, discounted at the cost of capital; no value tonight
Graham Number--The most a defensive investor pays for the earnings and book value per share; no value tonight
Graham Growth--Graham's growth formula: EPS × (8.5 + 2 × growth), adjusted for bond yields; no value tonight
Lynch--EPS × the earnings growth rate (PEG of 1), growth capped at 25%; no value tonight
GLS Growth--EPS compounded ten years at the blended growth rate, discounted back at 15% a year; no value tonight
10 Cap--Owner's earnings (operating cash flow less maintenance capex) capitalised at 10%; no value tonight
Payback Time--Eight years of compounded free cash flow: the price at which the business pays for itself; no value tonight
DDM--Dividend discount model: next year's dividend ÷ (10% − 3% growth); needs a dividend; no value tonight
EPV--Earnings power value: current EPS capitalised at 9% with no growth; no value tonight
Zombie (liquidation)0.5644-74%Current assets less all liabilities, per share: the balance-sheet floor. Not in the average
Wall St target3.50+62%Analysts' average 12-month price target. Not in the average

Quality and financial health

Financial health is weak: NAUT passes 3 of the nine Piotroski tests. Our screens drop the stock at the health rule; a low score is often the reason a stock looks cheap on the valuation models. The GLS Moat score is low at 1.4 out of 10, which says the ten-year record of revenue, earnings, margins and returns on capital has been inconsistent - growth and shocks rather than steady compounding.

Returns on capital are thin or negative - ROIC -31.6%, ROE -37.6%, ROA -30.9% - with debt at 0.19 times equity and negative free cash flow.

Nautilus Biotechnolgy, Inc. pays no dividend, so the DDM model does not apply and a covered-call holder earns only the premium and any price gain. Revenue comes mainly from Grant Revenue 92%, Service Revenue 8% (quarter Q2 FY2026).

Institutional ownership scores 5/10, insider activity 1/10 and Congressional trading 5/10 on the GLS smart-money scales.

Piotroski F-score3 / 9ROIC-31.6%
GLS Moat1.4 / 10ROE-37.6%
Debt / equity0.19ROA-30.9%
Free-cash-flow yield-18.9%Payout ratio0%
Institutions5 / 10Insiders · Congress1 · 5 / 10

Wheel Score 40: Weak

NAUT scores 40 out of 100 on the Wheel Score, in the Weak band (under 50). Value 13/25, Health 7/20, Moat 2/15, Premium 5/20, Stability 14/20. The score is not a judgement on the company; it says the price, quality and premium do not line up for selling puts on it today.

Implied volatility is 136%, far above the range the wheel strategy is built for. The premium looks generous; the Wheel Score gives it only 5 of 20 Premium points because moves of that size can blow through any strike. Chain open interest is 27,149 contracts across all expiries - enough for the wheel at normal size.

Volume runs at 8.5M shares a day on a market cap of $275M, with a beta of 0.87; the Stability part of the Wheel Score gives that 14 of 20.

PartPointsFrom
Value13 / 250% margin of safety
Health7 / 20Piotroski 3/9
Moat2 / 15moat 1.4/10
Premium5 / 20implied volatility 136%
Stability14 / 208.5M shares/day, $275M cap, beta 0.87

The Wheel Score ranks ~7,400 US stocks for selling cash-secured puts and covered calls; it is updated nightly and is not a recommendation. The walkthrough lesson shows how the score fits into a trade, start to finish.

Upcoming events

Nautilus Biotechnolgy, Inc. reports earnings on 26 Oct 2026 (before the open) - inside the 14-day window the Sunday Scan avoids, because a put sold now would carry the report's gap risk.

Earnings, dividend, IPO, split and economic calendars for the whole market, filterable to your watchlists.

Similar stocks in Biotechnology

The 12 companies below are the closest to Nautilus Biotechnolgy, Inc. by market cap within the Biotechnology industry, each with its own fact sheet; the Compare page puts up to eight of them side by side.

StockCloseFair valueMoSWheelMkt cap
OCGN
Ocugen, Inc.
0.8137--35Weak$276M
IPSC
Century Therapeutics, Inc.
1.502.67+44%45Weak$272M
FULC
Fulcrum Therapeutics, Inc.
3.673.01-22%30Weak$280M
ABEO
Abeona Therapeutics Inc.
4.650.9983-366%35Weak$265M
EYPT
EyePoint Pharmaceuticals, Inc.
3.14--37Weak$263M
CABA
Cabaletta Bio, Inc.
1.550.4921-215%18Weak$263M
PALI
Palisade Bio, Inc.
1.482.39+38%39No options$258M
VCRE
Vicore Pharma Holding AB
9.082.35-287%10No options$256M
BNTC
Benitec Biopharma Inc.
8.462.68-216%17Weak$295M
NWBO
Northwest Biotherapeutics, Inc.
0.1500--30No options$256M
IKT
Inhibikase Therapeutics, Inc.
1.831.41-30%16No options$255M
VNDA
Vanda Pharmaceuticals Inc.
4.22--43Weak$255M

⚖ Compare NAUT with 7 of them   All Healthcare stocks →

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Questions about NAUT

Is NAUT undervalued right now?

The GLS models could not value NAUT (the company lost money over the last twelve months, EPS -0.45 and it pays no dividend), so there is no fair value or margin of safety to compare the price of 2.16 against.

What is the Wheel Score of NAUT and what does it mean?

NAUT scores 40 out of 100 (Weak). The Wheel Score blends the margin of safety (25 points), Piotroski health (20), the GLS moat (15), the option premium on offer (20) and trading stability (20) into one number that ranks stocks for the wheel strategy - selling cash-secured puts, then covered calls if assigned. 80 and above is Prime, 65-79 Good, 50-64 Fair, under 50 Weak.

What is the GLS fair value for NAUT?

None of the nine GLS models produced a positive value for NAUT (the company lost money over the last twelve months, EPS -0.45 and it pays no dividend), so there is no GLS fair value tonight.

When does Nautilus Biotechnolgy, Inc. report earnings next?

The next earnings report is due on 26 Oct 2026 (before the open), 10 days from the data date of 16 Oct 2026. The Calendars page lists every upcoming report with its time of day.

Does NAUT have listed options, and how liquid are they?

Yes. The nightly snapshot found 70 listed contracts with 27,149 open interest across all expiries and implied volatility of 136% on the near-the-money contracts. The Options scanner lists the cash-secured put and covered call set-ups with premium and annualised yield worked out.

Data as of 16 Oct 2026: prices and fundamentals from Financial Modeling Prep, option data from Polygon; valuations, scores and the Wheel Score by GLS Equity's models, run nightly. Prices in USD; the close shown is the previous session's. Everything on this page is general information produced by automated models from third-party data - not a recommendation to buy, sell or trade any security or option, and not financial advice. Past performance is not indicative of future results. GLS Equity provides data and tools, not financial advice.