Stock fact sheet · data as of

Vaxcyte, Inc. (PCVX): fair value, margin of safety and Wheel Score

Healthcare · Biotechnology · United States · Speculative / Distressed

Close67.55
GLS fair value-no model value
Margin of safety-
Wheel Score45Weakcapped at 45
Health0/9Piotroski F-score
Moat0.5/10GLS 10-year score
Market cap$10.4B1.5M shares a day
Implied vol.51%near-the-money, 20-60 d
P/E-EPS -7.37
Dividend yieldnone
Beta1.23moves more than the market
Next earnings3 Nov 2026in 18 days (after the close)

Is PCVX undervalued?

At 67.55 (close of 16 Oct 2026), PCVX has no GLS fair value: every one of the nine models needs a positive input (the company lost money over the last twelve months, EPS -7.37 and it pays no dividend), so the margin of safety is blank and the Wheel Score cannot be computed. Our screens leave the stock out at the first rule. What can be said from the nightly row is below.

The nightly engine files PCVX under Speculative / Distressed - negative earnings or a Piotroski score of 3 or less - which caps its Wheel Score at 45 and keeps it out of the Sunday Scan.

Nine valuation models for PCVX

Each model turns the latest filed numbers into a value per share; the GLS fair value is the simple average of the ones that produce a positive number. The last two rows are shown for reference and never enter the average. The Quote page lets you switch any model off and add your own margin of safety.

ModelValuevs priceWhat it measures
DCF--Present value of the projected free cash flows, discounted at the cost of capital; no value tonight
Graham Number--The most a defensive investor pays for the earnings and book value per share; no value tonight
Graham Growth--Graham's growth formula: EPS × (8.5 + 2 × growth), adjusted for bond yields; no value tonight
Lynch--EPS × the earnings growth rate (PEG of 1), growth capped at 25%; no value tonight
GLS Growth--EPS compounded ten years at the blended growth rate, discounted back at 15% a year; no value tonight
10 Cap--Owner's earnings (operating cash flow less maintenance capex) capitalised at 10%; no value tonight
Payback Time--Eight years of compounded free cash flow: the price at which the business pays for itself; no value tonight
DDM--Dividend discount model: next year's dividend ÷ (10% − 3% growth); needs a dividend; no value tonight
EPV--Earnings power value: current EPS capitalised at 9% with no growth; no value tonight
Zombie (liquidation)8.26-88%Current assets less all liabilities, per share: the balance-sheet floor. Not in the average
Wall St target122.33+81%Analysts' average 12-month price target. Not in the average

Quality and financial health

Vaxcyte, Inc. scores only 0 of 9 on the Piotroski F-score, which fails the Sunday Scan's "6 or more" rule. A reading this low means several of the basic tests - positive earnings, positive operating cash flow, falling debt, no new share issuance - are not met. A GLS Moat score of 0.5/10 is a weak reading: the ten-year history the score grades (revenue, EPS, book value, margins, cash flow, share count, ROIC) has not been steady, so the Moat part of the Wheel Score contributes little.

Returns on capital are thin or negative - ROIC -26.3%, ROE -28.5%, ROA -25.2% - with debt at 0.09 times equity and negative free cash flow.

Vaxcyte, Inc. pays no dividend, so the DDM model does not apply and a covered-call holder earns only the premium and any price gain. Revenue comes mainly from Pneumococcal Conjugate Vaccine 100% (quarter Q2 FY2022).

Institutional ownership scores 10/10, insider activity 1/10 and Congressional trading 10/10 on the GLS smart-money scales; the last recorded Congressional buy was on 16 Jul 2026.

Piotroski F-score0 / 9ROIC-26.3%
GLS Moat0.5 / 10ROE-28.5%
Debt / equity0.09ROA-25.2%
Free-cash-flow yield-11.6%Payout ratio0%
Institutions10 / 10Insiders · Congress1 · 10 / 10

Wheel Score 45: Weak

With a Wheel Score of 45 Vaxcyte, Inc. sits in the Weak band, capped at 45 because the engine files it as Speculative / Distressed. The parts - Value 13/25, Health 0/20, Moat 1/15, Premium 20/20, Stability 19/20 - show where: Health (0/20) scores lowest.

Implied volatility is 51% on the near-the-money contracts 20-60 days out - inside the 35-60% range the Wheel Score pays full marks for: enough premium to be worth selling, not so much that the risk is unpaid. The option chain is deep: 128,184 contracts of open interest across all expiries, which means tight fills at most strikes.

Volume runs at 1.5M shares a day on a market cap of $10.4B, with a beta of 1.23 - a high beta, so the stock tends to move more than the market and a strike can be gapped through; the Stability part of the Wheel Score gives that 19 of 20.

PartPointsFrom
Value13 / 250% margin of safety
Health0 / 20Piotroski 0/9
Moat1 / 15moat 0.5/10
Premium20 / 20implied volatility 51%
Stability19 / 201.5M shares/day, $10.4B cap, beta 1.23

The Wheel Score ranks ~7,400 US stocks for selling cash-secured puts and covered calls; it is updated nightly and is not a recommendation. The walkthrough lesson shows how the score fits into a trade, start to finish.

Upcoming events

The next earnings report is due on 3 Nov 2026 (after the close), 18 days away; a 30-45-day put sold today would expire after it, which is worth weighing against the premium.

Earnings, dividend, IPO, split and economic calendars for the whole market, filterable to your watchlists.

Similar stocks in Biotechnology

The 12 companies below are the closest to Vaxcyte, Inc. by market cap within the Biotechnology industry, each with its own fact sheet; the Compare page puts up to eight of them side by side.

StockCloseFair valueMoSWheelMkt cap
IBRX
ImmunityBio, Inc.
10.00--45Weak$10.6B
MDGL
Madrigal Pharmaceuticals, Inc.
459.812,351.92+80%45Weak$10.6B
BMRN
BioMarin Pharmaceutical Inc.
56.0524.83-126%59Fair$10.8B
KRYS
Krystal Biotech, Inc.
330.00294.13-12%61Fair$9.8B
TWST
Twist Bioscience Corporation
148.16--45Weak$9.8B
TXG
10x Genomics, Inc.
73.1019.50-275%38Weak$9.5B
TECH
Bio-Techne Corporation
72.5019.15-279%62Fair$11.4B
CAI
Caris Life Sciences, Inc.
31.7618.13-75%48Weak$9.0B
KYMR
Kymera Therapeutics, Inc.
108.140.2471-43656%40Weak$8.9B
SMMT
Summit Therapeutics Inc.
15.130.2422-6147%32Weak$12.1B
CYTK
Cytokinetics, Incorporated
63.92--45Weak$8.9B
PTGX
Protagonist Therapeutics, Inc.
136.2838.39-255%51Fair$8.8B

⚖ Compare PCVX with 7 of them   All Healthcare stocks →

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Questions about PCVX

Is PCVX undervalued right now?

The GLS models could not value PCVX (the company lost money over the last twelve months, EPS -7.37 and it pays no dividend), so there is no fair value or margin of safety to compare the price of 67.55 against.

What is the Wheel Score of PCVX and what does it mean?

PCVX scores 45 out of 100 (Weak). The Wheel Score blends the margin of safety (25 points), Piotroski health (20), the GLS moat (15), the option premium on offer (20) and trading stability (20) into one number that ranks stocks for the wheel strategy - selling cash-secured puts, then covered calls if assigned. 80 and above is Prime, 65-79 Good, 50-64 Fair, under 50 Weak.

What is the GLS fair value for PCVX?

None of the nine GLS models produced a positive value for PCVX (the company lost money over the last twelve months, EPS -7.37 and it pays no dividend), so there is no GLS fair value tonight.

When does Vaxcyte, Inc. report earnings next?

The next earnings report is due on 3 Nov 2026 (after the close), 18 days from the data date of 16 Oct 2026. The Calendars page lists every upcoming report with its time of day.

Does PCVX have listed options, and how liquid are they?

Yes. The nightly snapshot found 386 listed contracts with 128,184 open interest across all expiries and implied volatility of 51% on the near-the-money contracts. The Options scanner lists the cash-secured put and covered call set-ups with premium and annualised yield worked out.

Data as of 16 Oct 2026: prices and fundamentals from Financial Modeling Prep, option data from Polygon; valuations, scores and the Wheel Score by GLS Equity's models, run nightly. Prices in USD; the close shown is the previous session's. Everything on this page is general information produced by automated models from third-party data - not a recommendation to buy, sell or trade any security or option, and not financial advice. Past performance is not indicative of future results. GLS Equity provides data and tools, not financial advice.