Stock fact sheet · data as of

Palvella Therapeutics, Inc. (PVLA): fair value, margin of safety and Wheel Score

Healthcare · Biotechnology · United States · Speculative / Distressed

Close122.58
GLS fair value4.711 of 9 models
Margin of safety-2501%price above fair value
Wheel Score40Weakout of 100
Health3/9Piotroski F-score
Moat0.4/10GLS 10-year score
Market cap$1.8B383k shares a day
Implied vol.54%near-the-money, 20-60 d
P/E-EPS -4.30
Dividend yieldnone
Beta-0.17moves less than the market
Next earnings10 Nov 2026in 25 days (before the open)

Is PVLA undervalued?

At 122.58 (close of 16 Oct 2026), PVLA trades 2501% over the GLS average fair value of 4.71, with 0 of 1 models above the price. The stock earns none of the Wheel Score's Value points at this price. That is a statement about price against trailing fundamentals, not about the company's prospects - the Wall Street View and the Growth tab on the Quote page carry the forward numbers.

The average is built from just 1 models (DCF) - the rest returned nothing because an input they need (dividends, free cash flow, book value) is zero or negative - so treat it with more caution than usual.

The nightly engine files PVLA under Speculative / Distressed - negative earnings or a Piotroski score of 3 or less - which caps its Wheel Score at 45 and keeps it out of the Sunday Scan.

Nine valuation models for PVLA

Each model turns the latest filed numbers into a value per share; the GLS fair value is the simple average of the ones that produce a positive number. The last two rows are shown for reference and never enter the average. The Quote page lets you switch any model off and add your own margin of safety.

ModelValuevs priceWhat it measures
DCF4.71-96%Present value of the projected free cash flows, discounted at the cost of capital
Graham Number--The most a defensive investor pays for the earnings and book value per share; no value tonight
Graham Growth--Graham's growth formula: EPS × (8.5 + 2 × growth), adjusted for bond yields; no value tonight
Lynch--EPS × the earnings growth rate (PEG of 1), growth capped at 25%; no value tonight
GLS Growth--EPS compounded ten years at the blended growth rate, discounted back at 15% a year; no value tonight
10 Cap--Owner's earnings (operating cash flow less maintenance capex) capitalised at 10%; no value tonight
Payback Time--Eight years of compounded free cash flow: the price at which the business pays for itself; no value tonight
DDM--Dividend discount model: next year's dividend ÷ (10% − 3% growth); needs a dividend; no value tonight
EPV--Earnings power value: current EPS capitalised at 9% with no growth; no value tonight
Zombie (liquidation)1.90-98%Current assets less all liabilities, per share: the balance-sheet floor. Not in the average
Wall St target229.00+87%Analysts' average 12-month price target. Not in the average

Quality and financial health

Palvella Therapeutics, Inc. scores only 3 of 9 on the Piotroski F-score, which fails the Sunday Scan's "6 or more" rule. A reading this low means several of the basic tests - positive earnings, positive operating cash flow, falling debt, no new share issuance - are not met. A GLS Moat score of 0.4/10 is a weak reading: the ten-year history the score grades (revenue, EPS, book value, margins, cash flow, share count, ROIC) has not been steady, so the Moat part of the Wheel Score contributes little.

Returns on capital are thin or negative - ROIC -145.8%, ROE -149.1%, ROA -70.0% - with debt at 0.02 times equity and negative free cash flow.

Palvella Therapeutics, Inc. pays no dividend, so the DDM model does not apply and a covered-call holder earns only the premium and any price gain.

Institutional ownership scores 10/10, insider activity 1/10 and Congressional trading 5/10 on the GLS smart-money scales.

Piotroski F-score3 / 9ROIC-145.8%
GLS Moat0.4 / 10ROE-149.1%
Debt / equity0.02ROA-70.0%
Free-cash-flow yield-2.1%Payout ratio0%
Institutions10 / 10Insiders · Congress1 · 5 / 10

Wheel Score 40: Weak

With a Wheel Score of 40 Palvella Therapeutics, Inc. sits in the Weak band. The parts - Value 0/25, Health 7/20, Moat 1/15, Premium 20/20, Stability 13/20 - show where: Value (0/25) scores lowest.

Implied volatility is 54% on the near-the-money contracts 20-60 days out - inside the 35-60% range the Wheel Score pays full marks for: enough premium to be worth selling, not so much that the risk is unpaid. Chain open interest is 3,172 contracts across all expiries - enough for the wheel at normal size.

Volume runs at 383k shares a day on a market cap of $1.8B, with a beta of -0.17 - a low beta, so day-to-day moves are smaller than the market's; the Stability part of the Wheel Score gives that 13 of 20.

PartPointsFrom
Value0 / 25-2501% margin of safety
Health7 / 20Piotroski 3/9
Moat1 / 15moat 0.4/10
Premium20 / 20implied volatility 54%
Stability13 / 20383k shares/day, $1.8B cap, beta -0.17

The Wheel Score ranks ~7,400 US stocks for selling cash-secured puts and covered calls; it is updated nightly and is not a recommendation. The walkthrough lesson shows how the score fits into a trade, start to finish.

Upcoming events

The next earnings report is due on 10 Nov 2026 (before the open), 25 days away; a 30-45-day put sold today would expire after it, which is worth weighing against the premium.

Earnings, dividend, IPO, split and economic calendars for the whole market, filterable to your watchlists.

Similar stocks in Biotechnology

The 12 companies below are the closest to Palvella Therapeutics, Inc. by market cap within the Biotechnology industry, each with its own fact sheet; the Compare page puts up to eight of them side by side.

StockCloseFair valueMoSWheelMkt cap
VIR
Vir Biotechnology, Inc.
10.41--45Weak$1.8B
ZYME
Zymeworks Inc.
24.77--45Weak$1.8B
SRPT
Sarepta Therapeutics, Inc.
16.83--45Weak$1.8B
XERS
Xeris Biopharma Holdings, Inc.
9.776.45-51%41Weak$1.8B
URGN
UroGen Pharma Ltd.
36.58--45Weak$1.8B
XNCR
Xencor, Inc.
23.39--39Weak$1.7B
BHVN
Biohaven Ltd.
11.43--41Weak$1.7B
MESO
Mesoblast Limited
13.95--45Weak$1.8B
TRVI
Trevi Therapeutics, Inc.
12.060.1068-11195%39Weak$1.7B
SEPN
Septerna Inc
36.3246.79+22%45Weak$1.7B
GENB
Generate Biomedicines, Inc.
13.06--45Weak$1.7B
NUVB
Nuvation Bio Inc.
4.753.07-55%38Weak$1.7B

⚖ Compare PVLA with 7 of them   All Healthcare stocks →

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Questions about PVLA

Is PVLA undervalued right now?

No: at 122.58 the stock trades 2501% above the GLS average fair value of 4.71 (data as of 16 Oct 2026), well beyond what trailing earnings, cash flow and book value support.

What is the Wheel Score of PVLA and what does it mean?

PVLA scores 40 out of 100 (Weak). The Wheel Score blends the margin of safety (25 points), Piotroski health (20), the GLS moat (15), the option premium on offer (20) and trading stability (20) into one number that ranks stocks for the wheel strategy - selling cash-secured puts, then covered calls if assigned. 80 and above is Prime, 65-79 Good, 50-64 Fair, under 50 Weak.

What is the GLS fair value for PVLA?

4.71 per share as of 16 Oct 2026 - the simple average of the 1 valuation models (out of nine: DCF, Graham Number, Graham Growth, Lynch, GLS Growth, 10 Cap, Payback Time, DDM and EPV) that produced a positive value. The models run every night on the latest filings; the Quote page lets you switch any of them off and add a margin of safety of your own.

When does Palvella Therapeutics, Inc. report earnings next?

The next earnings report is due on 10 Nov 2026 (before the open), 25 days from the data date of 16 Oct 2026. The Calendars page lists every upcoming report with its time of day.

Does PVLA have listed options, and how liquid are they?

Yes. The nightly snapshot found 288 listed contracts with 3,172 open interest across all expiries and implied volatility of 54% on the near-the-money contracts. The Options scanner lists the cash-secured put and covered call set-ups with premium and annualised yield worked out.

Data as of 16 Oct 2026: prices and fundamentals from Financial Modeling Prep, option data from Polygon; valuations, scores and the Wheel Score by GLS Equity's models, run nightly. Prices in USD; the close shown is the previous session's. Everything on this page is general information produced by automated models from third-party data - not a recommendation to buy, sell or trade any security or option, and not financial advice. Past performance is not indicative of future results. GLS Equity provides data and tools, not financial advice.