Stock fact sheet · data as of

Ascendis Pharma A/S (ASND): fair value, margin of safety and Wheel Score

Healthcare · Biotechnology · Denmark · ADR · High Growth

Close226.62
GLS fair value267.557 of 9 models
Margin of safety+15%price below fair value
Wheel Score70Goodout of 100
Health6/9Piotroski F-score
Moat1.7/10GLS 10-year score
Market cap$14.1B404k shares a day
Implied vol.47%near-the-money, 20-60 d
P/E17.2EPS 13.20
Dividend yieldnone
Beta0.37moves less than the market
Next earnings11 Nov 2026in 26 days (before the open)

Is ASND undervalued?

ASND closed at 226.62 on 16 Oct 2026, 15% below the GLS average fair value of 267.55 from 7 models (2 of them above the price). That is a moderate margin of safety: the stock passes the "below fair value" rule of the Sunday Scan, and the Wheel Score gives it 19 of the 25 Value points.

The 7 models disagree widely: Graham Number gives 76.80 while GLS Growth gives 808.30. A spread that wide means the average is sensitive to which methods you trust; the model table below shows where each one lands, and the Quote page lets you switch any of them off.

The nightly engine files ASND under High Growth: revenue and earnings growing fast enough that the growth-based models carry the valuation.

Nine valuation models for ASND

Each model turns the latest filed numbers into a value per share; the GLS fair value is the simple average of the ones that produce a positive number. The last two rows are shown for reference and never enter the average. The Quote page lets you switch any model off and add your own margin of safety.

ModelValuevs priceWhat it measures
DCF--Present value of the projected free cash flows, discounted at the cost of capital; no value tonight
Graham Number76.80-66%The most a defensive investor pays for the earnings and book value per share
Graham Growth383.13+69%Graham's growth formula: EPS × (8.5 + 2 × growth), adjusted for bond yields
Lynch139.81-38%EPS × the earnings growth rate (PEG of 1), growth capped at 25%
GLS Growth808.30+257%EPS compounded ten years at the blended growth rate, discounted back at 15% a year
10 Cap110.80-51%Owner's earnings (operating cash flow less maintenance capex) capitalised at 10%
Payback Time207.32-9%Eight years of compounded free cash flow: the price at which the business pays for itself
DDM--Dividend discount model: next year's dividend ÷ (10% − 3% growth); needs a dividend; no value tonight
EPV146.70-35%Earnings power value: current EPS capitalised at 9% with no growth
Zombie (liquidation)-5.71-103%Current assets less all liabilities, per share: the balance-sheet floor. Not in the average
Wall St target311.17+37%Analysts' average 12-month price target. Not in the average

Quality and financial health

Financial health is average - ASND passes 6 of the nine Piotroski tests, which passes the Sunday Scan's "6 or more" rule. The Financials tab on the Quote page shows which tests fail. The GLS Moat score is low at 1.7 out of 10, which says the ten-year record of revenue, earnings, margins and returns on capital has been inconsistent - growth and shocks rather than steady compounding.

Returns on capital are thin or negative - ROIC -30.9%, ROE 134.6%, ROA -16.8% - with debt at -5.35 times equity and a free-cash-flow yield of 2.7%.

Ascendis Pharma A/S pays no dividend, so the DDM model does not apply and a covered-call holder earns only the premium and any price gain.

Institutional ownership scores 10/10, insider activity 2/10 and Congressional trading 5/10 on the GLS smart-money scales.

Piotroski F-score6 / 9ROIC-30.9%
GLS Moat1.7 / 10ROE134.6%
Debt / equity-5.35ROA-16.8%
Free-cash-flow yield2.7%Payout ratio0%
Institutions10 / 10Insiders · Congress2 · 5 / 10

Wheel Score 70: Good

ASND scores 70 out of 100 on the Wheel Score (Good band, 65-79). The score blends the margin of safety (Value, 19/25), Piotroski health (13/20), the GLS moat (3/15), the option premium on offer (20/20) and how easily the stock trades (16/20). Moat (3/15) is the part holding the score back.

Implied volatility is 47% on the near-the-money contracts 20-60 days out - inside the 35-60% range the Wheel Score pays full marks for: enough premium to be worth selling, not so much that the risk is unpaid. Chain open interest is 12,427 contracts across all expiries - enough for the wheel at normal size.

Volume runs at 404k shares a day on a market cap of $14.1B, with a beta of 0.37 - a low beta, so day-to-day moves are smaller than the market's; the Stability part of the Wheel Score gives that 16 of 20.

PartPointsFrom
Value19 / 2515% margin of safety
Health13 / 20Piotroski 6/9
Moat3 / 15moat 1.7/10
Premium20 / 20implied volatility 47%
Stability16 / 20404k shares/day, $14.1B cap, beta 0.37

The Wheel Score ranks ~7,400 US stocks for selling cash-secured puts and covered calls; it is updated nightly and is not a recommendation. The walkthrough lesson shows how the score fits into a trade, start to finish.

Upcoming events

The next earnings report is due on 11 Nov 2026 (before the open), 26 days away; a 30-45-day put sold today would expire after it, which is worth weighing against the premium.

Earnings, dividend, IPO, split and economic calendars for the whole market, filterable to your watchlists.

Similar stocks in Biotechnology

The 12 companies below are the closest to Ascendis Pharma A/S by market cap within the Biotechnology industry, each with its own fact sheet; the Compare page puts up to eight of them side by side.

StockCloseFair valueMoSWheelMkt cap
NBIX
Neurocrine Biosciences, Inc.
136.95236.51+42%87Prime$13.9B
JAZZ
Jazz Pharmaceuticals plc
214.42253.97+16%80Prime$13.9B
HALO
Halozyme Therapeutics, Inc.
121.5184.14-44%62Fair$13.8B
BBIO
BridgeBio Pharma, Inc.
67.13--45Weak$13.1B
EXEL
Exelixis, Inc.
62.83105.86+41%94Prime$15.8B
SMMT
Summit Therapeutics Inc.
15.130.2422-6147%32Weak$12.1B
TECH
Bio-Techne Corporation
72.5019.15-279%62Fair$11.4B
BMRN
BioMarin Pharmaceutical Inc.
56.0524.83-126%59Fair$10.8B
MDGL
Madrigal Pharmaceuticals, Inc.
459.812,351.92+80%45Weak$10.6B
IBRX
ImmunityBio, Inc.
10.00--45Weak$10.6B
PCVX
Vaxcyte, Inc.
67.55--45Weak$10.4B
KRYS
Krystal Biotech, Inc.
330.00294.13-12%61Fair$9.8B

⚖ Compare ASND with 7 of them   All Healthcare stocks →

Screen the whole market the same way

A free GLS Equity account gets you nightly fair value and the Wheel Score on ~7,400 US stocks, a watchlist, the scanner preview and the Sunday Scan - the same eight-rule screen, emailed every week. Pro adds the full put and call scanners, unlimited watchlists with alerts and the trade journal.

Start free See the Sunday Scan

Questions about ASND

Is ASND undervalued right now?

By the GLS models, moderately: at 226.62 the stock trades 15% below the average fair value of 267.55 (data as of 16 Oct 2026).

What is the Wheel Score of ASND and what does it mean?

ASND scores 70 out of 100 (Good). The Wheel Score blends the margin of safety (25 points), Piotroski health (20), the GLS moat (15), the option premium on offer (20) and trading stability (20) into one number that ranks stocks for the wheel strategy - selling cash-secured puts, then covered calls if assigned. 80 and above is Prime, 65-79 Good, 50-64 Fair, under 50 Weak.

What is the GLS fair value for ASND?

267.55 per share as of 16 Oct 2026 - the simple average of the 7 valuation models (out of nine: DCF, Graham Number, Graham Growth, Lynch, GLS Growth, 10 Cap, Payback Time, DDM and EPV) that produced a positive value. The models run every night on the latest filings; the Quote page lets you switch any of them off and add a margin of safety of your own.

When does Ascendis Pharma A/S report earnings next?

The next earnings report is due on 11 Nov 2026 (before the open), 26 days from the data date of 16 Oct 2026. The Calendars page lists every upcoming report with its time of day.

Does ASND have listed options, and how liquid are they?

Yes. The nightly snapshot found 528 listed contracts with 12,427 open interest across all expiries and implied volatility of 47% on the near-the-money contracts. The Options scanner lists the cash-secured put and covered call set-ups with premium and annualised yield worked out.

Data as of 16 Oct 2026: prices and fundamentals from Financial Modeling Prep, option data from Polygon; valuations, scores and the Wheel Score by GLS Equity's models, run nightly. Prices in USD; the close shown is the previous session's. Everything on this page is general information produced by automated models from third-party data - not a recommendation to buy, sell or trade any security or option, and not financial advice. Past performance is not indicative of future results. GLS Equity provides data and tools, not financial advice.